Growth HormoneModerate Evidence

GHRP-6

Also known as: Growth Hormone Releasing Peptide-6

First synthetic GHRP with strong appetite-stimulating effects alongside GH release.

Benefits

Conditions

Evidence

Clinical trials, extensive research as first GHRP+ studies

Source

Synthetic hexapeptide ghrelin mimetic

Gabriel Brain Score

Moderate

Overview

First synthetic GHRP with strong appetite-stimulating effects alongside GH release.

Mechanism of Action

Activates ghrelin receptor (GHS-R1a) for GH secretion, potent appetite stimulation via ghrelin pathway, moderate cortisol and prolactin increase, synergizes with GHRH for enhanced GH pulse.

Key Benefits

✓GH and IGF-1 elevation
✓Strong appetite stimulation
✓Muscle growth support
✓Enhanced recovery
✓Improved sleep
✓Anti-inflammatory effects

Clinical Applications

Growth hormone deficiencyCachexia and wasting syndromesPoor appetiteRecovery from injury or illnessAge-related GH decline

Dosing Guidelines

Subcutaneous injection

Typical Dose100-300 mcg

Frequency1-3 times daily

Duration8-12 weeks

* Dosing should be individualized. Always consult with a qualified healthcare practitioner.

Research & Evidence

Evidence Level

Moderate

Studies

Clinical trials, extensive research as first GHRP

Summary

Well-characterized GH secretagogue. Clinical evidence for GH elevation. Strongest appetite effects of GHRP family. Useful when appetite stimulation is desired.

Safety Information

Potential Side Effects

•Significant increased hunger
•Water retention
•Numbness/tingling
•Cortisol and prolactin elevation

Contraindications

Active cancer
Pregnancy
Breastfeeding

Interactions

⚠Synergistic with GHRH analogs

Quick Facts

CategoryGrowth Hormone

SourceSynthetic hexapeptide ghrelin mimetic

Legal StatusResearch compound, not FDA approved

Gabriel Brain Score

77/ 100

Source Your Protocol

Our preferred peptide partner offers lab-tested, COA-verified peptides with optional physician oversight. Sourced from US-regulated facilities.

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