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Also known as: Cathelicidin, hCAP-18
Human antimicrobial peptide with broad-spectrum activity against bacteria, fungi, and viruses.
Benefits
6
Conditions
6
Evidence
Extensive in vitro and preclinical studies, limited human trials+ studies
Source
Naturally occurring human cathelicidin, synthesized therapeutically
Gabriel Brain Score
Moderate
Human antimicrobial peptide with broad-spectrum activity against bacteria, fungi, and viruses.
Disrupts microbial membranes via carpet-like mechanism, binds LPS to neutralize endotoxins and block TLR4, inhibits biofilm formation, exhibits immunomodulatory effects through chemokine induction, promotes wound healing via TGF-β pathway.
* Dosing should be individualized. Always consult with a qualified healthcare practitioner.
Extensive in vitro and preclinical studies, limited human trials
Well-characterized antimicrobial mechanisms in vitro. Limited human clinical data. Strong preclinical evidence for infection control and wound healing.
Broad class of innate immune peptides with antimicrobial, immunomodulatory, and wound-healing properties representing next-generation anti-infectives.
Family of small cationic antimicrobial peptides that form first line of innate immune defense.
Multifunctional iron-binding glycoprotein with antimicrobial, immunomodulatory, and anti-inflammatory properties.