Hormonal

Pregnenolone

"Mother hormone" precursor to all steroid hormones (DHEA, progesterone, testosterone, estrogen, cortisol)

Gabriel Score

68/ 100Good

CategoryHormonal

Applications5 conditions

FormsPregnenolone (micronized)

How it works

"Mother hormone" precursor to all steroid hormones (DHEA, progesterone, testosterone, estrogen, cortisol)

Typical Dosage

10-50mg/day (individualized based on testing)

Used for

Memory declineFatigueLow hormone levelsMood disordersStress

Practical Guide

Available Forms

Pregnenolone (micronized)

Natural Food Sources

•Produced from cholesterol (not a food)

Dosing should be individualized. Consult a qualified healthcare practitioner.

The Science

Evidence Base

Good68/100

Precursor to all steroid hormones; enhances memory; requires monitoring; may affect multiple hormone pathways

Works Well With

DHEA (downstream)Progesterone (downstream)

Safety Profile

Interactions

May interact with hormone therapies
May affect downstream hormones unpredictably

Contraindications

Hormone-sensitive cancers
Seizure disorders

Trusted Brands

Pure EncapsulationsLife ExtensionThorneDouglas Labs

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CategoryHormonal

Applications5

Gabriel Score68/100

Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.

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Pregnenolone

Practical Guide

Available Forms

Natural Food Sources

The Science

Evidence Base

Works Well With

Safety Profile

Trusted Brands

Have questions about Pregnenolone?

Build Your Protocol

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Melatonin

DIM (Diindolylmethane)

Myo-Inositol

Ready to explore natural options?

Pregnenolone

Practical Guide

Available Forms

Natural Food Sources

The Science

Evidence Base

Works Well With

Safety Profile

Trusted Brands

Have questions about Pregnenolone?

Build Your Protocol

Related Supplements

Melatonin

DIM (Diindolylmethane)

Myo-Inositol

Ready to explore natural options?