Neuropathy Recovery Protocol

Peripheral neuropathy affects 30+ million Americans. Causes: Diabetes (most common), B12 deficiency (especially metformin use), chemotherapy (platinum agents, taxanes), alcohol, hypothyroidism, autoimmune. Symptoms: Numbness, tingling, burning pain, typically feet/hands (stocking-glove distribution). Nerve damage hard to reverse but can stop progression and improve symptoms. Alpha-lipoic acid has strongest evidence - multiple RCTs in diabetic neuropathy showing symptom improvement. Dosing 600mg+ daily. Antioxidant and improves nerve blood flow. B12 crucial - methylcobalamin form better for nerve healing, many neuropathy patients deficient (especially on metformin). Benfotiamine (fat-soluble B1) specific for diabetic complications. Acetyl-L-carnitine helps mitochondria in nerves. Blood sugar control is foundation in diabetic neuropathy - every 1% A1C reduction reduces neuropathy risk 40%. Tight control can reverse early neuropathy. Pain management challenging - gabapentin, pregabalin, duloxetine are conventional options, CBD oil emerging alternative. Nerve regeneration is slow (1mm/day axon growth) - takes months. Combination approach best.