Herbs

Berberine

Activates AMPK; improves insulin sensitivity, modulates gut microbiome, antimicrobial

Gabriel Score

88/ 100Excellent

CategoryHerbs

Applications6 conditions

FormsBerberine HCl

How it works

Activates AMPK; improves insulin sensitivity, modulates gut microbiome, antimicrobial

Typical Dosage

500mg 2-3x/day with meals (1000-1500mg/day total)

Used for

Type 2 diabetesPCOSMetabolic syndromeHyperlipidemiaSIBOHypertension

Practical Guide

Available Forms

Berberine HCl

Natural Food Sources

•Not typically a food (from herbs like goldenseal, barberry)

Dosing should be individualized. Consult a qualified healthcare practitioner.

The Science

Evidence Base

Excellent88/100

"Nature's Metformin"; clinically effective for blood sugar; take with meals; may cause GI upset initially

Works Well With

ChromiumAlpha lipoic acidMilk thistleProbiotics

Safety Profile

Interactions

May potentiate diabetes and blood pressure meds
Inhibits CYP3A4
May affect gut flora

Contraindications

Pregnancy
Breastfeeding

Trusted Brands

ThornePure EncapsulationsIntegrative TherapeuticsLife Extension

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CategoryHerbs

Applications6

Gabriel Score88/100

Educational purposes only. Consult a qualified healthcare provider before starting any supplement protocol.

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Berberine

Practical Guide

Available Forms

Natural Food Sources

The Science

Evidence Base

Works Well With

Safety Profile

Trusted Brands

Have questions about Berberine?

Build Your Protocol

Related Supplements

Turmeric/Curcumin

Ashwagandha (Withania somnifera)

Milk Thistle (Silybum marianum)

Ready to explore natural options?

Berberine

Practical Guide

Available Forms

Natural Food Sources

The Science

Evidence Base

Works Well With

Safety Profile

Trusted Brands

Have questions about Berberine?

Build Your Protocol

Related Supplements

Turmeric/Curcumin

Ashwagandha (Withania somnifera)

Milk Thistle (Silybum marianum)

Ready to explore natural options?